
低密度脂蛋白受体的诱导降解蛋白抗体
产品名称: 低密度脂蛋白受体的诱导降解蛋白抗体
英文名称: MYLIP
产品编号: bs-9674R
产品价格: null
产品产地: 北京
品牌商标: BIOSS
更新时间: 2025-07-02T08:48:39
使用范围: WB=1:100-500,ELISA=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200,
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E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.