FAS Rabbit Polyclonal Antibody
产品名称： FAS Rabbit Polyclonal Antibody
英文名称： FAS Rabbit Polyclonal Antibody
产品编号： K000322P
产品价格： null
产品产地： 北京市通州区马驹桥
品牌商标： solarbio
更新时间： 2025-10-28T13:20:45
使用范围：
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市北京经济技术开发区环科中路16号26幢3层301
- 邮编 :
- 所在区域 : 北京
- 电话 : 181****6239 点击查看
- 传真 : 点击查看
- 邮箱 : 3193328036@qq.com
- 二维码 : 点击查看
Anti-FAS Polyclonal Antibody
品牌：solarbio | 货号：K000322P
商品货号： 商品品牌： 规格 基本售价： 选择规格 K000322P-50ul solarbio 50ul 960.00元 K000322P-100ul solarbio 100ul 1600.00元
英文名称 Anti-FAS Polyclonal Antibody 别名 ALPS1A;APO-1;APT1;CD95;FAS1;FASTM;TNFRSF6 应用 WB IHC 稀释比例 WB 1:500-2000. IHC 1:50-100. 蛋白分子量 38kDa Gene ID 355 保存 Store at -20°C. Avoid freeze / thaw cycles. 储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. 纯化方法 Affinity purification 亚型 IgG 免疫原 A synthetic peptide of human FAS 性状 液体 Public
Immunogen
Range A synthetic peptide of human FAS Subcellular
Locations Cell membrane Secreted Single-pass type I membrane
protein Swiss Prot P25445 克隆类型 Polyclonal Antibody 背景资料 The protein encoded by this gene is a member of the TNF-
receptor superfamily. This receptor contains a death
domain. It has been shown to play a central role in the
physiological regulation of programmed cell death, and
has been implicated in the pathogenesis of various
malignancies and diseases of the immune system. The
interaction of this receptor with its ligand allows the
formation of a death-inducing signaling complex that
includes Fas-associated death domain protein (FADD),
caspase 8, and caspase 10. The autoproteolytic processing
of the caspases in the complex triggers a downstream
caspase cascade, and leads to apoptosis. This receptor has
been also shown to activate NF-kappaB, MAPK3/ERK1, and
MAPK8/JNK, and is found to be involved in transducing
the proliferating signals in normal diploid fibroblast and T
cells. Several alternatively spliced transcript variants have
been described, some of which are candidates for
nonsense-mediated mRNA decay (NMD). The isoforms
lacking the transmembrane domain may negatively
regulate the apoptosis mediated by the full length isoform.
| 商品货号： | 商品品牌： | 规格 | 基本售价： | 选择规格 |
|---|---|---|---|---|
| K000322P-50ul | solarbio | 50ul | 960.00元 | |
| K000322P-100ul | solarbio | 100ul | 1600.00元 |
| 英文名称 | Anti-FAS Polyclonal Antibody |
|---|---|
| 别名 | ALPS1A;APO-1;APT1;CD95;FAS1;FASTM;TNFRSF6 |
| 应用 | WB IHC |
| 稀释比例 | WB 1:500-2000. IHC 1:50-100. |
| 蛋白分子量 | 38kDa |
| Gene ID | 355 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human FAS |
| 性状 | 液体 |
| Public Immunogen Range | A synthetic peptide of human FAS |
| Subcellular Locations | Cell membrane Secreted Single-pass type I membrane protein |
| Swiss Prot | P25445 |
| 克隆类型 | Polyclonal Antibody |
| 背景资料 | The protein encoded by this gene is a member of the TNF- receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform. |