乙酰化赖氨酸抗体-辣根过氧化物酶
产品名称： 乙酰化赖氨酸抗体-辣根过氧化物酶
英文名称： Acetyl Lysine Antibody, HRP
产品编号： ICP0381
产品价格： null
产品产地： 进口
品牌商标： 进口
更新时间： null
使用范围：
- 联系人 :
- 地址 : 上海市嘉定区叶城路1288号
- 邮编 :
- 所在区域 : 上海
- 电话 : 187****6455 点击查看
- 传真 : 点击查看
- 邮箱 : yanhuibio@163.com
Product Description: Affinity purified rabbit polyclonal anti-acetylated lysine antibody (anti-AcK) was developed using a unique technique that utilize the acetylated KLH as immunogen. The purified antibody was conjugated to horseradish peroxidase (HRP) via reductive amination. Direct label of primary antibody will avoid the use of secondary antibodies therefore eliminating the interference of the 2nd antibody-conjugates.
Species: Rabbit
Formulation: 250 µg/mL antibody stored in PBS, pH 7, with 50% glycerol.
Storage & Stability: Store product at –20 ℃. One year from date of shipping.
Immunogen: Acetylated KLH conjugates.
Purification: The antibody was purified on acetyl-lysine agarose.
Conjugation: Reductive amination, HRP/Ab molar ratio: 2:1.
Application(s): For western blotting direct and immunohistochemistry.
Specificity: Recognize proteins acetylated on lysine residues.
Tested: acetylated histone, acetylated BSA, and acetylated MBP, no reaction to the non-acetylated proteins.
Scientific Description: Acetylation of lysine is an important reversible modification. The activity of some proteins is controlled by this process. Histone acetyltransferases (HATs) acetylate the conserved amino-terminal domains of the four core histones (H2A, H2B, H3 and H4) that contain lysines residues. Histone deacetylases (HDACs) removes the acetyl group from the same residue.Acetylation/deacetylation of histones results in cell signaling processes that include gene activity, cell growth, differentiation and apoptosis. In cancer and polyglutamine diseases, the regulation of protein acetylation/deacetylation is impaired.
References: 1. Hassig, C.A. et al. Curr. Opin. Chem. Biol. 1997. 1, 3, 300-308. 2. Allfrey, V. G. et al. Proc. Natl. Acad. Sci. USA 1964, 51, 786-794. 3. Hughes, R.E. Curr. Biol. 2002. 12, R141-R143.
| Anti-5-HT（5-hydroxytryptamine） | 5-羟色胺抗体 |
| Anti-5-HTR1A (5-HT1A (5-hydroxytryptamine/serotonin receptor 1A; 5HT1a; ADRBRL1; ADRB2RL1; HTR1A) | 5-羟色胺受体1A抗体 |
| Anti-5-HTR1B (5-hydroxytryptamine/serotonin receptor 1B) | 5-羟色胺受体1B(5-HT/serotoninR1B)抗体 |
| Anti-5-HTR2B(5-hydroxytryptamine(serotonin)receptor 2B) | 5-羟色胺受体2B(5-HT/serotoninR2B)抗体 |
| Anti-5-HTR2A | 5-羟色胺受体2A抗体 |
| Anti-5-HTT/SERT(Serotoninreuptake transporter) | 5-羟色胺转运蛋白抗体 |
| Anti-5-HTR3(5-hydroxytryptamine (serotonin) receptor 3a) | 5-羟色胺受体3抗体 |
| Anti-5-HTR4(5 hydroxytryptamine serotonin receptor 4) | 5-羟色胺受体4抗体 |
| Anti-5-LOX (5-lipoxygenase) | 5-脂氧合酶抗体 |
| Anti-8-OHdG（8-Hydroxy-2'-deoxyguanosine; 8-Hydroxydeoxyguanosine） | 8-羟基脱氧鸟苷抗体 |
| Anti-A2AR/Adenosine A2A-R(A2A adenosine receptor) | 腺苷A2A受体抗体 |
| Anti-AACT-α1 (chymotrypsin-Alpha1) | α-1抗胰糜蛋白酶抗体 |
| Anti-AAK1(AP2 associated protein kinase 1) | AP2关联激酶1抗体 |
| Anti-AARS2（alanyl tRNA synthetase 2） | 丙氨酰tRNA合成酶2抗体 |
| Anti-AARS2(alanyl tRNA synthetase 2) | 丙氨酰tRNA合成酶2抗体 |